Heterogeneity of Monoclonal Antibodies(20)
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发布时间:2021-06-07
impairment of immunoreactivity.Biol Chem Hoppe Seyler366:361–366.
190.Danze PM,Tarjoman A,Rousseaux J,Fossati P, Dautrevaux M.1987.Evidence for an increased glycation of IgG in diabetic patients.Clin Chim Acta166:143–153.
191.Hammes HP,Kiefel V,Laube H,Federlin K.1990.
Impaired agglutination of IgM resulting from non-enzymatic glycation in diabetes mellitus.Diabetes Res Clin Pract9:37–42.
polla A,Fedele D,Aronica R,Garbeglio M, D’Alpaos M,Seraglia R,Traldi P.1997.Evaluation of IgG glycation levels by matrix-assisted laser desorption/ionization mass spectrometry.Rapid Commun Mass Spectrom11:1342–1346.
polla A,Fedele D,Garbeglio M,Martano L, Tonani R,Seraglia R,Favretto D,Fedrigo MA, Traldi P.2000.Matrix-assisted laser desorption/ ionization mass spectrometry,enzymatic diges-tion,and molecular modeling in the study of nonenzymatic glycation of IgG.J Am Soc Mass Spectrom11:153–159.
194.Dolhofer-Bliesener R,Gerbitz KD.1990.Impair-ment by glycation of immunoglobulin G Fc frag-ment function.Scand J Clin Lab Invest50:739–746.
195.Hennessey PJ,Black CT,Andrassy RJ.1991.
Nonenzymatic glycosylation of immunoglobulin
G impairs complementfixation.JPEN J Parenter
Enteral Nutr15:60–64.
196.Morin LG,Austin GE,Burkhalter A.1987.None-nzymatic glycation of immunoglobulins does not impair antigen-antibody binding.Clin Chem33: 692–694.
197.Morin LG,Austin GE,Rodey GE,Johnson JE.
1989.Nonenzymic glycation of human immuno-globulins does not impair their immunoreactivity.
Clin Chem35:1039–1042.
198.Menini T,Gugliucci A,Stahl AJ.1992.Polyclonal immunoglobulin M:Location of glycation sites.
Clin Chim Acta213:23–35.
199.Dolhofer-Bliesener R,Gerbitz KD.1990.Effect of nonenzymatic glycation on the structure of immunoglobulin G.Biol Chem Hoppe Seyler 371:693–697.
200.Sasaki Y,Mori T,Shiiki H,Dohi K,Ishikawa H.
1993.Non-enzymatic glycosylation of mouse monoclonal antibody reduces its binding activity to antigen.Clin Chim Acta220:119–121.
201.Kennedy DM,Skillen AW,Self CH.1994.Glyca-tion of monoclonal antibodies impairs their ability to bind antigen.Clin Exp Immunol98:245–251. 202.Vrdoljak A,Trescec A,Benko B,Hecimovic D, Simic M.2004.In vitro glycation of human immunoglobulin G.Clin Chim Acta345:105–111.
203.Jairajpuri DS,Fatima S,Saleemuddin M.2007.
Immunoglobulin glycation with fructose:A com-
parative study.Clin Chim Acta378:86–92.(Epub 2006Nov2006.)
204.Connell GE,Painter RH.1966.Fragmentation of immunoglobulin during storage.Can J Biochem 44:371–379.
205.Smith AM,Dowd AJ,Heffernan M,Robertson CD, Dalton JP.1993.Fasciola hepatica:A secreted cathepsin L-like proteinase cleaves host immuno-globulin.Int J Parasitol23:977–983.
206.Kong Y,Chung YB,Cho SY,Kang SY.1994.
Cleavage of immunoglobulin G by excretory-secre-tory cathepsin S-like protease of Spirometra man-soni plerocercoid.Parasitology109:611–621. 207.Berasain P,Carmona C,Frangione B,Dalton JP, Goni F.2000.Fasciola hepatica:Parasite-secreted proteinases degrade all human IgG subclasses: Determination of the specific cleavage sites and identification of the immunoglobulin fragments produced.Exp Parasitol99–110.
208.Gearing AJ,Thorpe SJ,Miller K,Mangan M, Varley PG,Dudgeon T,Ward G,Turner C,Thorpe R.2002.Selective cleavage of human IgG by the matrix metalloproteinases,matrilysin and stro-melysin.Immunol Lett81:41–48.
209.Turner MW,Bennich H.1968.Subfragments from the Fc fragment of human immunoglobulin G.
Isolation and physicochemical charaterization.
Biochem J107:171–178.
210.Matthews N,Stewart G,Stanworth DR.1971.
Characterisation of a new tryptic sub-fragment of human and rabbit IgG Fc fragment.Immuno-chemistry8:973–981.
211.Connell GE,Porter RR.1971.A new enzymic fragment(Facb)of rabbit immunoglobulin G.
Biochem J124:53.
212.Natvig JB,Turner MW.1971.Localization of Gm markers to different molecular regions of the Fc fragment.Clin Exp Immunol8:685–700.
213.Ellerson JR,Yasmeen D,Painter RH,Dorrington KJ.1972.A fragment corresponding to the C(H)2 region of immunoglobulin G(IgG)with comple-mentfixing activity.FEBS Lett24:318–322. 214.Ellerson JR,Yasmeen D,Painter RH,Dorrington KJ.1976.Structure and function of immunoglo-bulin domains.III.Isolation and characterization of a fragment corresponding to the Cgamma2 homology region of human immunoglobin G1.
J Immunol116:510–517.
215.Rao PE,Kroon DJ.1993.Orthoclone O KT3.Che-mical mechanisms and functional effects of degra-dation of a therapeutic monoclonal antibody.
Pharm Biotechnol5:135–158.
216.Paborji M,Pochopin NL,Coppola WP,Bogardus JB.1994.Chemical and physical stability of chi-meric L6,a mouse-human monoclonal antibody.
Pharm Res11:764–771.
217.Cordoba AJ,Shyong BJ,Breen D,Harris RJ.2005.
Non-enzymatic hinge region fragmentation of
DOI10.1002/jps JOURNAL OF PHARMACEUTICAL SCIENCES,VOL.97,NO.7,JULY2008
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