艾叶的化学成分_(4)

566沈 阳 药 科 大 学 学 报

-1

第27卷

5 0#0 6),andUVdetectionwavelengthwassetat324nm,attheflowrateof1 0mL%min,andthecol umntemperaturewassetat40 .ResultsThelinearrangeswas0 6 24 0 g%mL(r=0 9998)forum belliferone.Theaveragerecoverywas98 5%withRSDof1 9%.ConclusionsThemethodisaccurate,sensitivewithgoodreproducibilityandcouldbeusedforthedeterminationofthecontentofumbelliferoneinWikstroemiaindica(L.)C.A.Mey..

Keywords:Wikstroemiaindica(L.)C.A.Mey.;HPLC;umbelliferone;contentdetermination(上接第550页)

过它的结构,可是理化数据很少,尤其没有光谱数据。根据以上化学反应和波谱数据可确定该化合物为4 甲氧基 3 羟基苯酚(4 methoxyl 3 hydroxyphenol),为一新的天然产物。参考文献:

[1]吉双,张予川,刁云鹏,等.艾叶的化学成分[J].沈

阳药科大学学报,2009,26(8):617-619.

[2]MARCOJA,SANZ-CERVERAJF,MANGLANO

E,eta.lSesquiterpenelactonesfromIranianArtemisiaspecies[J].Phytochemistry,1993,34(6):1561-1564.

[3]尹锋,楼凤昌.佛手化学成分的研究[J].中国药学

杂志,2004,39(1):20-21.

[4]周光雄,王国平,杨永春,等.黄瑞香茎皮的化学成

分研究[J].中草药,2007,38(3):327-329.[5]张成刚,李伯刚,顾健,等.马蹄荷化学成分研究

[J].天然产物研究与开发,2003,15(4):308-309.[6]曹家庆,党权,付红伟,等.滇桂艾纳香化学成分的

分离与鉴定[J].沈阳药科大学学报,2007,24(10):615-617.

[7]吴斐华,梁敬钰,陈荣,等.毛平车前的化学成分和

保肝活性[J].中国天然药物,2006,4(6):435-439.

[8]STEPHENJA,LEONO.TheeffectofO methylation

onchemicalshiftsinthe1H NMRand1983,123:23-29.

[9]任东春,钱士辉,杨念云,等.明党参化学成分研究

[J].中药材,2008,31(1):47-49.

[10]SHAMMAM,STIVERLD.Twonewisoflavones

fromtheheartwoodofCladrastislutea:Cladrastinandcladrin[J].Tetrahedron,1969,25(17):3887-3893.

13

-1

C NMR

spectraofcyclicpolyols[J].CarbohydrateResearch,

ChemicalconstituentsfromtheFoliumArtemisiaeArgyi( )

JIShuang,LUGui rong,MENGDa li,LINing,LIXian

1

2

1

1

1

(1.SchoolofTraditionalChineseMateriaMedica,ShenyangPharmaceuticalUniversity,Shenyang110016,China;2.TiexiWomanandInfantHospitalofShenyang,Shenyang110023,China)

Abstract:ObjectiveToisolatetheconstituentsofFoliumArtemisiaeArgyiandidentifytheirstructures.MethodsThecompoundswereisolatedbychromatographyonsilicagelcolumn,SephadexLH 20,prepara tiveTLCandrecryztallization,andidentifiedonthebasisofphysico chemicalconstantsandspectralanaly sis.ResultsTencompoundswereidentifiedasisotanciloide(1),umbelliferone(2),daphnetin(3),eriodicty ol(4),rhamnetin(5),hispidulin(6),L 2 O methyl chiro inositol(7),stigmasterol(8),daucosterol(9)and4 methoxyl 3 hydroxyphenol(10).ConclusionsCompound10isanewlydiscoverednaturalproduc,tandcompounds1 5and7arefirstlyisolatedfromFoliumArtemisiaeArgy.iKeywords:FoliumArtemisiaeArgy;ichemicalconstituen;tstructureidentification