91. Jubran A, Tobin MJ. Pathophysiologic basis of acute respiratory distress in patients who fail

a trial of weaning from mechanical ventilation.Am J Respir Crit Care Med. 1997, 155:906–915.

92. Larca L, Greenbaum DM. Effectiveness of intensive nutritional regimes in patients who fail

to wean from mechanical ventilation. Crit Care Med，1982，10(5):297-300.

93. Lemaire F, Teboul JL, Cinotti L,et al. Acute left ventricular dysfunction during unsuccessful

weaning from mechanical ventilation. Anesthesiology, 1988, 69(2):171-9.

94. Girault C, Breton L, Richard J-C, et al: Mechanical effects of airway humidification devices

in difficult to wean patients. Crit care Med, 2003, 31:1306–1311.

95. Girault C, Daudenthun I, Chevron V, et al. Noninvasive ventilation as a systematic

extubation and weaning technique in acute-on-chronic respiratory failure: a prospective,randomized controlled study. Am J Respir Crit Care Med,1999,160(1):86–92.

96. 王辰，商鸣宇，黄克武，等.有创与无创序惯性通气治疗慢性阻塞性肺疾病所致严重呼

吸衰竭的研究. 中华结核和呼吸杂志,2000,23:389~390.

97. Kollef MH. The prevention of ventilator associated pneumonia. N Eng J Med, 1999,

340 :627-634.

98. Kollef MH. Avoidance of tracheal intubation as a strategy to prevent ventilator-associated

pneumonia. Intensive Care Med, 1999, 25:553-555.

99. Kramer B. Ventilator-associated pneumonia in critical ill patients. Ann Int

Med ,1999 ;130 :1027-1028.

100. Vitacca M, Ambrosino N,Clini E,et al. Physiological response to pressure support ventilation

delivered before and after extubation in patients not capable of totally spontaneous autonomous breathing. Am J Respir Crit Care Med,2001, 164(4):638-41.

101. A Collective Task Force Facilitated by the American College of Chest Physicians, the

merican Association for Respiratory Care, and the American College of Critical Care Medicine. Evidence-Based Guidelines for Weaning and Discontinuing Ventilatory Support. Respir Care,2002,47(1):69 –90.

102. Epstein SK, Ciubotaru RL,Wong JB. Effect of failed extubation on the outcome of

mechanical ventilation. Chest, 1997, 112(1):186-92.

103. Torres A, Gatell JM, Aznar E, et al. Re-intubation increases the risk of nosocomial

pneumonia in patients needing mechanical ventilation. Am J Respir Crit Care Med, 1995 ,152(1):137-41.

104. Ferrer M, Valencia M,Nicolas JM,et al. Early noninvasive ventilation averts extubation

failure in patients at risk: a randomized trial. Am J Respir Crit Care Med, 2006, 173(2):164-70.

105. Esteban A, Frutos-Vivar F, Ferguson ND, et al. Noninvasive positive-pressure ventilation for

respiratory failure after extubation. N Engl J Med, 2004, 350(24):2452-60.