The transcriptional regulatory repertoire of Corynebacterium(4)
发布时间：2021-06-06
176K.Brinkrolfetal./JournalofBiotechnology149 (2010) 173–182
Table1
FeaturesandphysiologicalrolesoftranscriptionregulatorsinCorynebacteriumglutamicumATCC13032.Codingregioncg0012cg0019cg0051cg0090cg0112cg0156cg0196cg0215cg0313cg0317cg0337cg0350cg0444cg0454cg0500cg0527cg0702cg0800cg0862
Alternativeidenti erNCgl0009NCgl0015NCgl0035NCgl0068NCgl0082NCgl0120NCgl0154NCgl0171NCgl0253NCgl0257NCgl0275NCgl0286NCgl0358NCgl0368NCgl0405NCgl0430NCgl0581NCgl0668NCgl0721
GenenamessuR––citBureRcysRiolRcspAlrparsR2whcAglxRramB–qsuRglyR–prpRmtrA
ProteinfamilyROKLysRAraC
ResponseregulatorMarRROKGntRColdAsnCArsRWhiBCrpHTHTetRLysRArsRLysRHTHResponseregulator
Numberoftargetgenesa
913471810132815055341134
EvidencebEPPEPEEEEEPEEPEEPEE
Regulatoryroleandphysiologicalfunctionoftranscriptionregulatorc
Activatorofsulfonateandsulfonateesterutilizationgenes
Activatorofmembraneproteingenecg0018ActivatorofABC-typetransportergenescg0052–cg0054
ActivatorofcitratetransportergenescitHandtctCBA
RepressorofureasegenesureABCEFGD
Dualregulatorofassimilatorysulfatereductiongenes
RepressorofinositolmetabolismgenesRepressorofmalatesynthasegeneaceB
ActivatorofaminoacidexportergenesbrnFERepressorofarsenitepermeasegenearsB2andarsenatereductasegenearsC2
RepressorofoxidativestressresponsegenesDualregulator(globalregulator)functioningasnetworkhub
Dualregulator(masterregulator)ofcarbonmetabolism
RepressorofMFS-typetransportergenescg0455andcg0456
ActivatorofquinateandshikimateutilizationgenesqsuABCD
ActivatorofserinehydroxymethyltransferasegeneglyA
Activatorofsecondarytransportergenecg0701ActivatorofpropionateutilizationgenesprpD2B2C2
Dualregulatorofgenesinvolvedincellmorphology,antibioticssusceptibilityandosmoprotection
ECFsigmafactor(masterregulator)involvedinglobalstressresponse
ActivatorofthioredoxingeneclustertrxBC-cwlM
ActivatorofpyridoxalphosphatesynthasegenespdxST
RepressorofABC-typetransportergenescg0977andcg0978
Repressor(masterregulator)ofnitrogenmetabolism
Repressorofsecondarytransportergenecg0992Repressorofsecondarytransportergenecg1033RepressorofMmpL-typetransportergenecg1054
Repressorofgenesforironprotein
RepressorofMFS-typetransportergenecg1212RepressorofNADbiosynthesisgenesnadAC-cg1214
ECFsigmafactorinvolvedinresponsestocellsurfacestresses
Repressorofhydroxyquinolpathwaygenescg1310andcg1311
Dualregulator(masterregulator)ofrespirationRepressorofriboseuptakeanduridineutilizationgenes
ActivatorofaminoacidexportergenelysERepressorofleucineandtryptophanbiosynthesisgenes
Repressorofuridineutilizationandriboseuptakegenes
Repressorofquinoneoxidoreductasegeneqor2RepressorofargininebiosynthesisgenesRepressorofABC-typetransportergenescg1652–cg1649andcg1653
RepressorofarsenitepermeasegenearsB1andarsenatereductasegenesarsC1andarsC1’Repressorofaconitasegeneacn
Repressorofiron–sulfurclusterbiogenesisgenes
RepressorofpyrimidinebiosynthesisgenesRepressorofABC-typetransportergenescg1832–cg1834
cg0876cg0878cg0897cg0979cg0986cg0993cg1032cg1053cg1120cg1211cg1218cg1271cg1308cg1340cg1410cg1425cg1486cg1547cg1552cg1585cg1648cg1704cg1738cg1765cg1817cg1831
NCgl0733NCgl0734NCgl0753NCgl0823NCgl0829NCgl0836NCgl0869NCgl0886NCgl0943NCgl1019NCgl1025NCgl1075NCgl1110NCgl1138NCgl1203NCgl1215NCgl1261NCgl1312NCgl1317NCgl1345NCgl1401–
NCgl1483NCgl1504NCg1551lNCgl1563
sigHwhcEpdxR–amtR–––ripA–nrtRsigE–arnRrbsRlysGltbRuriRqorRargRrpiRarsR1acnRsufRpyrR–
SigmafactorWhiBGntRPadRTetRArsRArsRTetRAraCArsRNrtRsigmafactorTetRCOG2345LacILysRIclRLacICOG1733ArgRRpiRArsRTetRArsRPyrRArsR
583233922218141379191029632743
EPEEEPEEEPPEEEEEEEEEPEEEEP
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