体外受精-胚胎移植周期中血清性激素水平对胚胎
时间:2025-04-30
时间:2025-04-30
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论著
体外受精~胚胎移植周期中血清性激素水平
对胚胎着床的影响
张金玉
【摘要】
葛明晓郭新宇于妍谢素嫣李文玲
目的探讨IVF周期中血清雌、孕激素水平及其比值与胚胎着床关系。方法行n下一ET治疗
38例患者共38个周期(其巾妊娠组17例、未孕组21例),用化学发光法测定HCG日、胚胎移植日、胚胎种植
窗血清孕酮、雌二醇水平;统计学方法t检验。结果两组黄体支持黄体酮剂量差异无统计学意义(P>o.05),
妊娠组与未孕组HCG13、胚胎移植日、种植窗血清雌、孕激素水平升降变化趋势一致,但妊娠组以上三个时期雌二醇水平高于未孕组,但差异无统计学意义(P>0.05),种植窗孕酮高于未孕组(P<0.05)}妊娠组种植窗与移植日B/P值明显低于未孕组,差异无统计学意义(P>0.05)。结论响妊娠结局,血清E2/P比值过高可能影响胚胎着床。
【关键词】
体外受精一胚胎移植;雌二醇;孕酮
IVF—ET周期患者自身黄体功能影
Effectof
Serlllrl
estradiolandprogesteronelevelsduringlutealphase
in—vitrofertilizationcycle
on
embryohnplantationin
ZANGJinyu,GEMingxiao,GUOXinyu,eta1.
(Centerofassistedreproduction,DepartmentofObstetricsandGynecology,MilitaryGeneralHospital
ofGuangzhou,Guangzhou510010,China)
[Abstract]
Objective
Tostudytherelationshipbetweenthelevelof
serul'n
Estradiol(E2),Progesterone38
patientsinvolvedinthis
(P)andF-e/PduringlutealphaseandembryoimplantationinlvFcycle.Methods
studyweredividedintotWOgroups:pregnancygroup(n=17)andnon—pregnancygroup(n221).SerumBandPlevelsweredetermined
On
theHCGadministrationday,embryotransferdayand3daysafter
embryo
transfer(elTl-
bryoimplantationwindow).Resultslevelswere
at
The¥anleprogesteronesupportwasfoundinthetwogroups.SerumPand岛
on
the&alrlevariabletendency
HCGadministrationday,embryotransferdayand
embryo
implantation
windowinthetwogroups.SerumPandE2levelswerehigherinpregnancygroupthanthoseinnon—pregnancy
groupP
0n
embryotransferdayandembryoimplantationwindown,but
no
significantdifferenceswerefound.Serum
levelsinpregnancygroupwerehigherthanthoseinthenon—pregnancygrouponembryoimplantationwindow(P<
oil
o.05);theratioofE2/P
group
the
embryotransferdayandembryoimplantationwindowwere10werinthepregnancy
no
thanthenon—pregnancygroup,butsignificantdifferenceswerefoundinthetwogroups(P>O.05).
rate
Conclusion
Lutealfunctionofthepatientitselfmayaffectedtheclinicalpregnancy
inIvFcycle。higherratioof
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