Combinatorial rules of icosahedral capsid growth(11)
时间:2025-07-12
时间:2025-07-12
A model of growth of icosahedral viral capsids is proposed. It takes into account the diversity of hexamers' compositions, leading to definite capsid size. We show that the observed yield of capsid production implies a very high level of self-organization
Nowanaturalquestioncanbeasked:whatcomesnext?InordertogrowcapsidswithT-numbersgreaterthan7,onehastointroducenewtypesofhexamersthatwouldneversticktopentamers,butbeingabletoassociatethemselveswithcertainsidesoftheformermaximallydi erentiatedhexam-ers.TheresultisshownintheFig.8
below:
Figure8:ThebuildingformulafortheT=9capsid
Thecorrespondinga nitytableisgivenbelow:
acena
00000
10000
00010
00000
00100
00001
01000
00000
00000
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